Group Leader

Dr. Andrey KLYMCHENKO

Research Director of CNRS (DR1), HdR

Tel: +33 (0) 368 85 42 55
E-mail: andrey.klymchenko@unistra.fr

website

I direct the work on fluorescent molecules and nanoparticles for bioimaging and theranostics.

Permanent Staff

Dr. Andreas REISCH

Maître de conferences (tenured assistant professor) in biophysics

Tel : +33 (0) 368 85 42 66
E-mail: reisch@unistra.fr

website

I am working on ultrabright fluorescent polymer nanoparticles and their use in bioimaging.

Dr. Mayeul COLLOT

CNRS researcher
Tel : +33 (0) 368 85 42 66
E-mail: mayeul.collot@unistra.fr

website

My research focuses on the development of molecular and nanostructured fluorescent probes based on different systems, which provide efficient fluorescent turn-on effects or spectral changes upon detection of cellular events (variation of pH, calcium concentration, reductive environment, ligand/receptor interaction, etc).

Dr. Philippe CHABERT

CNRS Research Engineer (IR2), HdR
Tel : +33 (0) 3 68 85 42 43
E-mail: philippe.chabert@unistra.fr

Projects: Organic synthesis and natural compounds.

PhD students & Postdocs

Fei LIU

PhD student
E-mail: liufei3an@gmail.com

Project: I work on nanoemulsions based pH controlled drug delivery and insitu uptake.

Sophie BOU

PhD student
E-mail: s.bou@unistra.fr

Project: Fluorescent labeling of biocompatible polymers for bioimaging. Collaborative project with the company MedinCell.

Dmytro DANYLCHUK

PhD student
E-mail: danilchukdi@gmail.com

Project: Stimuli-responsive self-assembled fluorescent organic nanoparticles: synthesis and biological applications. The study includes synthesis of organic NPs, displaying sensitivity towards pH, redox potential or presence of specific molecules with further applications for imaging and theranostics.

Sylvie EGLOFF

PhD student
E-mail: sylvie.egloff@unistra.fr

Project: Detection and imaging of biomolecular cancer markers in living cells using fluorescent organic nanoparticles.
The objective of my thesis is the detection of cancer markers in living cells using custom designed fluorescent organic nanoparticles, which includes studies of their interactions with target receptors, their internalization, the detection of intracellular RNA and cytotoxicity.

Anne RUNSER
PhD student
E-mail: anne.runser@unistra.fr

Project: Fluorescent polymer nanoparticles for bioimaging.

Caterina SEVERI

PhD student
E-mail: severi.caterina@etu.unistra.fr

Project: Synthesis of light-harvesting nano-antennas and their applications for bioimaging.

My PhD project focuses on development of nano-antennas based on polymeric nanoparticles and their potential applications, such as photocatalysis, enhanced cellular internalization, and detection of species of biologic interest.

Tkhe Kyong FAM

PhD student
E-mail: tkhe-kyong.fam@unistra.fr

My PhD project, supported by “BightRiboProbes” ANR grant, aims to design and synthesize fluorogenic probes of different colours, to characterize their phothophysical properties. Moreover, my work includes the fluorescence microscopy studies of the probes capacity to detect targeted RNA in live cells.

Nina MELNYCHUK

PhD student
E-mail: nina.melnychuk@etu.unistra.fr

Project: Synthesis of fluorescent organic nanoparticles for amplified detection of biomolecules.The objectives of the project are to develop organic nanoparticles that turn on their fluorescence in response to a single mRNA and apply them for detection of mRNA cancer markers in cell lysates.

Dr. Yudhistira TESLA

Postdoctoral researcher
E-mail: tesla@unistra.fr

Project: Nanoantenna.

Dr. Ilya APARIN

Marie Curie Postdoctoral researcher
E-mail: aparin@unistra.fr

website

Project: Design of light-harvesting DNA-nanoprobes with ratiometric signal amplification for fluorescence imaging of live cells (DNANanoProbes). I'm working on development of fluorescent polymeric nanoparticles decorated with DNA-probes for imaging in living cells and gene silencing.

Dr. Anila HOSKERE ASHOKA

Postdoctoral researcher
E-mail: anil.hoskere@gmail.com

Project: Development of hybrid fluorescent materials for sensing and medical applications.

Former members

Dr. Adarsh NAGAPPAN PILLAI

Marie Curie Post-Doctoral Researcher
E-mail: adarsh.nagappan-pillai@unistra.fr

Project: Luminescent Polymer Nanoparticles for FRET Mediated Ratiometric Oxygen Sensing (NanoOxySens).

Dr. Redouane BOUCHAALA

Postdoctoral researcher
E-mail: r.bouchaala@hotmail.com

Project: The development of biocompatible nanoparticles (nanoemulsion) as new nanoscale carriers, enabling the encapsulation of high and medium hydrophobic drugs, without leakage and their controlled release. In addition, this project aims to test /validate the therapeutic potential of these prodrugs in relevant mouse models, and to assess specific tumor/metastasis targeting using real time non-invasive bioimaging.

Dr. Doriane HEIMBURGER

PhD student
E-mail: doriane.heimburger@gmail.com

website

Project: Synthesis of small and ultrabright fluorescent polymer nanoparticles for molecular and cellular imaging. The aim of PhD project is to obtain ultrasmall (10-40 nm) polymer NPs, characterized by uniform size, exceptional fluorescence brightness, controlled number of functional groups at the surface as well as minimal non-specific interactions in the cellular context.

Dr. Ashokkumar PICHANDI

Postdoctoral researcher
E-mail: ashokkumar.pichandi@unistra.fr

Project: The development of ultra-bright fluorescent polymeric nanoparticles for FRET applications and targeted bio-imaging in cells.

Dr. Jurga VALANCIUNAITE

Engineer
E-mail: jurga.valanciunaite@unistra.fr

Projects: Optical spectroscopy studies, fluorescence correlation spectroscopy and microscopy.

Dr. Youri ARNTZ
Tel: +33 (0)3 68 85 41 15
E-mail: youri.arntz@unistra.fr

Projects: Bio-nanotechnology and atomic force microscopy.